Standard operating procedure for curation and clinical interpretation of variants in cancer

Standard Operating Procedure: Clinical Commissioning Policy: Proton Beam Therapy for Cancer of the Prostate

Standard operating procedure for computing pangenome trees

We present the pan-genome tree as a tool for visualizing similarities and differences between closely related microbial genomes within a species or genus. Distance between genomes is computed as a weighted relative Manhattan distance based on gene family presence/absence. The weights can be chosen with emphasis on groups of gene families conserved to various degrees inside the pan-genome. The s...

Standard Operating Procedure: Clinical Commissioning Policy: Autologous chondrocyte implantation for osteochondral lesions of the talus (adults)

The IGS Standard Operating Procedure for Automated Prokaryotic Annotation

The Institute for Genome Sciences (IGS) has developed a prokaryotic annotation pipeline that is used for coding gene/RNA prediction and functional annotation of Bacteria and Archaea. The fully automated pipeline accepts one or many genomic sequences as input and produces output in a variety of standard formats. Functional annotation is primarily based on similarity searches and motif finding co...

Standard Operating Procedure: Clinical Commissioning Policy: The use of Stereotactic Ablative Radiotherapy (SABR) in the treatment of Prostate Cancer